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Skin prep and site choice still affect pen performance Even when the pen is used correctly, the injection site can change the experience

Like insulin, IGF-1 also exhibits blood sugar-lowering effects, although IGF-1 is not nearly as effective at decreasing blood glucose levels as insulin is, according to a 2004 report in the Journal of Clinical Investigation

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It notes the gastrointestinal effects are most common during titration and often improve with slower dose escalation managed by a provider